甘氨酸亚铁改善学龄儿童营养性贫血的效果观察

Observation on the efficacy of glycine chelated iron (II) in improving nutritional anemia in children

目的为观察甘氨酸亚铁改善儿童营养性贫血的效果.方法选择年龄在7～12岁之间的贫血儿童(选择指血血红蛋白含量＜120g/L),按血红蛋白含量随机将其分成安慰剂对照组(60人)和补充甘氨酸铁试食组(60人),观察期为1个月.结果儿童试食甘氨酸亚铁30天后的结果表明,口服甘氨酸亚铁一个月能使贫血儿童的血红蛋白含量显著升高,红细胞游离原卟啉含量显著降低,试食组自身前后比较,血红蛋白平均升高幅度＞10g/L,并且试食组试验后血红蛋白含量和红细胞游离原卟啉含量与对照组相比有显著的统计学差异.结论甘氨酸亚铁具有改善学龄儿童营养性贫血的作用.

Objective To observe the efficiency of glycine chelated iron （Ⅱ） on nutritional iron-deficient anemia. Method The iron-deficient anemic children （120 subjects）, aged 7 - 12 were randomly divided into two groups, one group as a control group given with a placeboes and another group treated with glycine chelated iron （Ⅱ） for one month. Results Compared with the control group, the addition of glycine chelated iron （Ⅱ） group had a significantly higher hemoglobin level （ 〉 10g/L） in whole blood and a lower free erythrocyte protoporphyrin （FEP） content. Conclusion The iron from glycine chelated iron （Ⅱ） have a role in improving nutritional iron-deficient anemia in children.