期刊文献+

环氧交联牛颈静脉带瓣管道的形态学和理化性能的研究

Morphologic and physiochemical properties of bovine jugular conduit with valves fixed with polyepoxy compound
下载PDF
导出
摘要 目的探讨环氧化合物交联牛颈静脉带瓣管道的外观形态,组织稳定性及流体物理性能的特征。方法取新鲜牛颈静脉带瓣管道24根,随机分为环氧化合物处理组(PC组,n=8),戊二醛处理组(GA组,n=8)及新鲜对照组(Control组,n=8)。分别测量各组处理前后管壁厚度,管腔外径及瓣膜的抗返流性能的变化。测定处理前后各组的组织含水量,热皱缩温度,组织断裂强度,断裂伸长率。结果PC组外观形态,管腔外径,瓣膜抗返流性能较对照组差异无显著性(P>0.05),GA组血管变硬,呈淡黄色,抗返流性能下降,与PC组相比差异有显著性(P<0.05)。PC组及GA组的组织含水量和断裂伸长率均低于Control组(P<0.05),PC组和GA组的热皱缩温度,断裂强度较Control组均升高(P<0.05);PC组组织断裂强度GA组比较差异无显著性。结论环氧化合物能有效交联牛颈静脉带瓣管道提高其组织的稳定性,且能较好的保护瓣膜的抗返流性能。 [Objective] To investigate the morphologic and mechanical properties of bovine jugular venous conduit with valves fixed with polyepoxy compound. [Methods] Twenty-four bovine jugular venous conduits with valves were divided into three groups and fixed with polyepoxy compound (PC group), glutaraldehyde (GA group) and Control group respectively. Morphologic and mechanical properties of three groups, including colour, thickness, diameter, moisture content, denaturation temperature, tensile strength,elongation at break and fixation index assay were studied. [Results] There were no difference in colour, wall thickness, diameter, tissue between PC and Control group, but significant difference between GA and PC group. The moisture content and elongation at break of PCgroup and GA group were lower than those of Control group (P 〈0.05), and PC group higher than those of GA group (P 〈0.05). The denaturation temperature of PC group and GA group were higher than that of Control group (P 〈0.05), but PC group lower than that of GA group. There were no diference in tensile strength between PC and GA. [Condusion] The polyepoxy compound fixed bovine jugular vein conduit can remain more natural and flexible, moreover it can effectively preserve the structure and the anti-reflow function of valves and improve the tissue stability and enhance the tension of bovine jugular conduit with valves.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2005年第18期2767-2769,2772,共4页 China Journal of Modern Medicine
关键词 颈静脉 环氧化合物 形态学 理化性能 bovine jugular venous conduit polyepoxy compound morphologic physiochemical
  • 相关文献

参考文献12

  • 1BREYMANN T, THIES WR, BOETHIG D, et al. Bovine valved venous xenograft for RVOT reconstruction:Results after 71 implantations[J]. Eur J Cardiothorac Surg, 2002, 21(4): 703-710.
  • 2COMO AF, HUMI M, GRIFFIN H, et al. Bovine jugular vein as fight ventricle-to-pulmonary artery valved conduit [J]. J Heart Valve Dis, 2002, 11(2): 242-247.
  • 3YOUNES BOUD JEMLINE, DAMIEN BONNET, CABRIELLA AGNOLETTI, et al. Aneurysm of the fight ventricular outflow following bovine valved venous conduit insertion [J]. Eur J of Cardio-Thoraeie Surgery, 2003, 23(1): 122-124.
  • 4THIERRY BOVE MDa, HELENE DEMANET MDa et al. Expected freedom from structural degeneration and patient outgrowth for the bovine jugular vein conduit: is it possible to calculate a safe rale for children?: Reply The Annals of Thoracic Surgery, 2003, 76(5): 2167-2168.
  • 5郭宇红,吴忠仕,胡建国,周新民,杨一峰.戊二醛固定的牛颈静脉带瓣管道的钙化实验研究[J].中国现代医学杂志,2004,14(8):90-92. 被引量:1
  • 6SHEN SH, SUNG HW, TU IL et al. Characterization of a polyepoxy compound fixed porcine heart valve bioprosthesis[J]. J Appl Biornater, 1994, 5: 159-162.
  • 7SHEN SH, SUNG HW, TU R, HATA C, et al. Characterization of a polyepoxy compound fixed porcine heart valve bioprcsthesis[J]. J Appl Biomat, 1994, 5: 159-162.
  • 8SUNG HW, SHIH, HSU CS, et al. Crosslink characteristics of porcine tendons-effect of fLxation with glutaraldehyde or epoxy[J].J Biomed Mater Rcs, 1996, 30: 361-367.
  • 9BOUDIEMLINE, DAMIEN BONNET, FRANCK ISERIN, et al.Use of bovine jugular vein to reconstruct the fight ventricular outflow tract early results [J]. J Thorac Cardiovasc Surg, 2003,126(2): 490-497.
  • 10吴忠仕,张竟超,程端,杨晓涵,陈金兰,胡建国.牛颈静脉带瓣管道结构特性及流体动力学的实验研究[J].湖南医科大学学报,2003,28(3):298-300. 被引量:29

二级参考文献12

  • 1Breymann T, Thies WR, Boethig D, et al. Bovine valved venous xenografts for RVOT reconstruction : Results after 71 implantations[ J]. Eur J Cardiothorac Surg,2002,21 (4) :703-710.
  • 2Como AF, Humi M, Griffin H ,et al. Bovine jugular vein as right ventricle-to-pulmonary artery valved conduit [ J ]. J Heart Valve Dis,2002,11 ( 2 ) :242-247.
  • 3Ichikawa Y, Noishiki Y, Kosuge T, et al. Use of a bovine jugular vein grit with natural valve for right ventricular outflow tract reconstruction : A one-year animal study[ J]. J Thorac Cardiovasc Surg, 1997,114(2) :224-233.
  • 4Ross DN, Somerville J. Correction of pulmonary atresia with a homograft aortic valve [J]. Lancet, 1966, 2(7497) : 1446-1447.
  • 5Dearani JA, Danielson GK, Puga FJ,et al. Late follow-up of 1095 patients undergoing operation for complex congenital heart disease utilizing pulmonary ventricle to pulmonary artery conduits[J]. Ann Thorac Surg, 2003, 75(2) : 399-411.
  • 6Niwaya K, Knott-Craig CJ, Lane MM, et al. Cryopreserved homograft valves in the pulmonary position: Risk analysis for inter-mediate-term failure[J]. J Thorac Cardiovasc Surg, 1999, 117(1) :141-147.
  • 7Chang Y, Tsai CC, Liang HC,et al. Reconstruction of the right ventricular outflow tract with a bovine jugular vein graft fixed with a naturally occurring crosslinking agent (genipin) in a canine model [J]. J Thorac Cardiovasc Surg, 2001,122(6) : 1208-1218.
  • 8Breymann T, Thies WR, Boethig D, et al. Bovine valved venous xenografts for RVOT reconstruction: results after 71 implantations[ J]. Eur J Cardiothorac Surg,2002, 21 (4) :703 -710.
  • 9Herijgers P, Ozaki S, Verbeken E, et al. Valved jugular vein segments for right ventricular outflow tract reconstruction in young sheep [ J ]. J Thorac Cardiovasc Surg, 2002,124 (4) :798 - 805.
  • 10Carpentier A, Nashef A, Carentier S, et al. Techniques for prevention of calcification of valvular bioprotheses[ J]. Circulation, 1984,70 (suppl Ⅱ ) :165-168.

共引文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部