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菲得欣治疗慢性阻塞性肺疾病急性发作的疗效观察 被引量:11

Effects of ambroxol in treating acute exacerbation of chronic obstructive pulmonary disease
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摘要 目的探讨菲得欣(氨溴索注射液)在慢性阻塞性肺疾病(chron ic obstructive pu lm onary d isease,COPD)急性发作中的治疗作用。方法COPD急性加重期患者60例,对照组(30例)仅给予抗生素及解痉平喘药物治疗,治疗组(30例)除上述治疗外,还给予菲得欣50m g ivgtt q12h,连用7天。比较治疗后第4、8日时两组的症状评分,并判定疗效。结果两组在治疗第4、8天时症状均较治疗前有所好转,治疗组症状在第4、8日较对照组改善明显(P<0.05)。结论菲得欣可有效改善COPD急性加重期患者的症状,改善睡眠质量,是有效辅助治疗药物之一。 Objective To study the effects of ambroxol in treating acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods, Sixty cases of AECOPD were included in this study, In the control group (30 cases), the patients were regularly treated. In the treatment group, in additional to the regular treatment, ambroxol were given with 50mg ivgtt q12h for 7 days, The scores of symptoms and the treatment effects were compared between the two groups. Results. The symptoms in the both groups improved the 4th day and the 8th day, when compared with thepre-treatment. The symptom improvements in the treatment group were significantly better than that of the control group (P〈0.05). Conclusion, Ambroxot was one of the effective assistant agents in AECOPD treatment, It can improve the symptoms and sleep quality of AECOPD patients,
作者 张腊梅
出处 《临床肺科杂志》 2005年第6期767-768,共2页 Journal of Clinical Pulmonary Medicine
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参考文献3

  • 1慢性阻塞性肺疾病诊治指南[J].中华结核和呼吸杂志,2002,25(8):453-460. 被引量:5103
  • 2朱元珏 陈文彬.呼吸病学[M].北京:人民卫生出版社,2002.609-616.
  • 3George CF, Bayliff CD Management of insomnia in patients with chronic obstructive pulmonary disease. Drugs, 2003, 63(4): 379-387.

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