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支气管哮喘与Th1/Th2失衡研究进展 被引量:22

Progress in research on relationship between bronchial asthma and Th1/Th2 imbalance
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摘要 许多研究表明,哮喘是一种免疫性疾病,其中T淋巴细胞控制着炎症反应[1].近年来的研究认为辅助性T淋巴细胞(T helper cell,Th)两种亚型Th1、Th2的失衡是哮喘发病的重要机制[2].
出处 《中西医结合学报》 CAS 2005年第5期403-407,共5页 Journal of Chinese Integrative Medicine
关键词 哮喘 T淋巴细胞 辅助诱导 白细胞介素类 asthma~ T-lymphocytes, helper-inducer~ interleukins
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参考文献31

  • 1刘亚君,陈良安,代华平,张波.中华医学会第六次全国呼吸系病学术会议纪要[J].中华结核和呼吸杂志,2001,24(1):8-11. 被引量:35
  • 2Lucey DR, Clerici M, Shearer GM. Type 1 and type 2cytokine dysregulation in human infectious, neoplastic,and inflammatory diseases [J]. Clin Microbiol Rev,1996, 9(4): 532-562.
  • 3Mosmann TR, Cherwinski H, Bond MW, et al. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins[J]. J Immunol, 1986, 136(7): 2348-2357.
  • 4Maggi E, Biswas P, Del-prefe G, et al. Accumulation of Th2-like helper T cells in the conjunctiva of patients with vernal conjunctivitis [J]. J Immunol, 1991, 146(4): 1169-1174.
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  • 6陈欣.白介素-12与支气管哮喘[J].国外医学(呼吸系统分册),2002,22(6):286-288. 被引量:7
  • 7孔祥永,贾天明.Th_2细胞和哮喘气道炎症[J].河南医学研究,2000,9(3):286-288. 被引量:3
  • 8吴健.BCG与变应性哮喘T_(H1)/T_(H2)平衡[J].国外医学(呼吸系统分册),2001,21(3):151-153. 被引量:28
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二级参考文献96

  • 1曾泽戎,崔德健,梁延杰,彭瑞云,王德文.哮喘豚鼠模型细支气管和肺组织的病理学研究[J].中华内科杂志,2001,40(3):158-161. 被引量:29
  • 2[1]Mosmann TR, Cherwinski H, Bond Mw, et al. Two types of murine helper T cell clone Definition accrding to profiles of lymphokine aclivilives and secreted protein.s [J]. J Immunol, 1986,136: 2348-2357.
  • 3[2]Maggi E,Biswas P, Del-prete G, et al. Accumulation of TH2-Like the conjunctive ofpatients with conjunctivitis [J]. Immunol,1991, 146:1169-1174.
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