期刊文献+

香草酸受体调节剂

Progresses in Vanilloid Receptor Modulators
下载PDF
导出
摘要 综述了近年来国内外香草酸受体调节剂的研究进展。香草酸受体是瞬时受体电位离子通道家族中的成员,为治疗疼痛的新靶点。 The latest progresses in vanilloid receptor modulators were reviewed. As the member of transient receptor potential family of ion channels, vanilloid receptor is the new target against pain.
出处 《药学进展》 CAS 2005年第9期409-416,共8页 Progress in Pharmaceutical Sciences
关键词 香草酸受体 镇痛 受体调节剂 Vanilloid receptor Analgesia Receptor modulator
  • 相关文献

参考文献32

  • 1Caterina M J, Schumacher M A, Tominaga M, et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway[J]. Nature, 1997,389(6653):816-824.
  • 2Gunthorpe M J, Benham C D, Randall A, et al. The diversity in the vanilloid (TRPV) receptor family of ion channels[J]. Trends Pharmacol Sci, 2002, 23(4):183-191.
  • 3Bevan S, Szolcsanyi J. Sensory neuron-specific actions of capsaicin: mechanisms and applications[J]. Trends Neurosci, 1990, 11(2):330-333.
  • 4Koplas P A, Rosenberg R L, Oxford G S. The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons[J]. J Neurosci, 1997, 17(20):3525-3537.
  • 5Yao J P, Nair M G, Ghandra A. Supercritical carbon dioxide extraction of scotch bonnet (capsicum annuum) and quantification of capsaicin and dihydrocapsaicin[J]. J Agric Food Chem, 1994,42(3):1303-1305.
  • 6Hisashi Segi, Shuji Yamada, Satoshi Kato, et al. Method for industrial purification of capsaicin[P]. US:5 955 631, 1999-09-21.
  • 7Harumi Kaga, Masakatsu Miura, Kazuhiko Orito. A facile procedure for synthesis of capsaicin[J]. J Org Chem, 1989,54(14):3477-3478.
  • 8Walpole C S J, Wrigglesworth R, Bevan S, et al. Analogues of capsaicin with agonist activity as novel analgesic agent; structure-activity studies.1.the aromatic "A-Region"[J]. J Med Chem, 1993,36(16):2362-2372.
  • 9Walpole C S J, Wrigglesworth R, Bevan S, et al. Analogues of capsaicin with agonist activity as novel analgesic agent; structure-activity studies.2.the amide bond "B-Region"[J]. J Med Chem, 1993,36(16):2373-2380.
  • 10Walpole C S J, Wrigglesworth R, Bevan S, et al. Analogues of capsaicin with agonist activity as novel analgesic agent; structure-activity studies.3.the Hydrophobic side-chain "C-Region"[J]. J Med Chem, 1993,36(16):2381-2390.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部