职业性三氯乙烯中毒死亡病例的调查

Investigation on an Occupational Trichloroethylene Poisoning with Death

目的探讨某五金制品厂三氯乙烯中毒病例的主要临床表现并分析其死亡原因。方法对该患者的工作场所空气中三氯乙烯浓度及病人的主要症状与体征,病人的血常规、尿常规和肝功能检查结果等临床资料进行调查分析。结果三氯乙烯中毒病人出现皮肤红斑、皮疹、巩膜黄染、发热等症状,肝功能明显异常,肝肿大,ALT264U/L,AST219.7U/L,T-BIL112μmol/L,患者因昏迷,呼吸、心跳停止而死亡。结论三氯乙烯中毒主要引起皮肤和肝脏损害,病情进展迅速,治疗不及时或治疗不当易导致死亡。

[ Objective] To study the major clinical manifestation of the trichloroethylene poisoning cases and the causes of death. [Methods] Investigation and analysis were carried out on the concentration of trichloroethylene on site and the major symptoms of the patients. Routine blood examination, urine examination and liver function were also done and analyzed. [ Results] Trichloroethylene poisoning patients were found with symptoms like red specks, skin rash, yellow sclera and fever. They were also found with obvious abnormal liver function, hepatomegaly, ALT 264 U/L,AST 219.7 U/L, T - BIL 112 μmol/L, and finally died of coma, respiration and heart failure. [ Conclusion] Trichloroethylene poisoning may mainly lead to skin and liver impairment with a rapid development. Improper or delayed treatment may lead to death.