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糖脂消对胰岛素抵抗高血压大鼠血脂水平的影响 被引量:1

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摘要 目的观察糖脂消对胰岛素抵抗高血压大鼠血脂水平的影响,探讨其作用机制。方法用高果糖饲料喂养♂SD大鼠造成胰岛素抵抗高血压大鼠模型,然后随机将其分为高果糖饲料及高果糖加低、高剂量的糖脂消组。通过测定各组收缩压(SBP)、空腹血糖(FBG)、空腹血清胰岛素(FINS)、瘦素(LP)、甘油三酯(TG)、胆固醇(TC)和高密度脂蛋白(HDLC),评估胰岛素抵抗(IR)等来探讨糖脂消对血脂水平的影响及其作用机制。结果糖脂消能有效调节血脂异常。结论糖脂消调脂的部分机理可能与其改善胰岛素抵抗,降低瘦素水平有关。
出处 《中成药》 CAS CSCD 北大核心 2005年第9期1097-1099,共3页 Chinese Traditional Patent Medicine
基金 天津市自然科学基金重点项目(项目编号023803611)
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