摘要
The polyoxometalate K6H[CoW11O39（CpTi）] （abbreviated as CoW11CpTi, Cp=η^5-C5H5） loaded nanosize-liposome complex has been prepared and structurally characterized by elemental analysis, IR and UV spectra. The particle size of the complex was distributed in the range of 100-250 nm with the average diameter of 132.6 nm. The result showed that the polyoxometalate retained the parent structure after being encapsulated by liposome and liposomal encapsulation increased the antitumoral activity of the polyoxometalate.
The polyoxometalate K6H[CoW11O39（CpTi）] （abbreviated as CoW11CpTi, Cp=η^5-C5H5） loaded nanosize-liposome complex has been prepared and structurally characterized by elemental analysis, IR and UV spectra. The particle size of the complex was distributed in the range of 100-250 nm with the average diameter of 132.6 nm. The result showed that the polyoxometalate retained the parent structure after being encapsulated by liposome and liposomal encapsulation increased the antitumoral activity of the polyoxometalate.
基金
Project supported by the National Natural Science Foundation of China （No. 20171011）, Chongqing Municipal Education Commision （No. kj05805）, and Chongqing Normal University （Nos. 05XSY001 and 05XLZ001）.Acknowledgements The authors are grateful to Liansheng S0NG and Gengyue ZHANG of Jilin Province Tumor Hospital, Changchun, for assaying the antitumoral activity.
