干烧黄芪鱼抗自由基和细胞调节信使NO作用的实验研究

Experimental Research into the Effect of the Deep Stewed Carp with Astragalus on SOD, GSH-PX, NO and NOS

用干烧黄芪鱼掺和到饲料中饲养实验性衰老小鼠40天,测定小鼠脑、肾超氧化物歧化酶(SOD)活力、小鼠肝谷胱甘肽过氧化物酶(GSH-Px)活力,小鼠睾丸、脑中一氧化氮(No)含量和睾丸、血清中一氧化氮合成酶(NOS)活力。结果表明:添加干烧黄芪鱼的实验组相比与空白对照组,在以上各项指标上均存有显著性或十分显著性差异。即药膳干烧黄芪鱼具有一定的抗自由基作用,并对雄性衰老小鼠生殖系统NO含量及NOS活力有一定影响。

We fed the controlled mice with the fodder mixed with deep stewed carp with astragalus with the aim to study its effect on the activity of SOD （superoxide dismmtase） in brain and kidney, the activity of GSH-PX in liver, the content of NO （nitricoxide） in testicle and brain and the activity of NOS （nitricoxide synthase） in testicle and serum. 40days later, the activities of SOD, GSH-PX, NO and NOS in the D-gal＇s aging mice were measured. The results show that there are obvious, even greatly obvious differences in the above indexes for D-gal controlled group fed with the fodder mixed with the deep stewed carp with astragalus by contrast to the blank group, which says that the medical diet - the deep stewed carp with astragalus can improve the activities of SOD and GSH-PX in D-gal＇s aging mice and has a certain effect on NO content and NOS activity in the testicle of D-gal＇s aging mice.