不能触及肿块的多中心乳腺癌（临床病理分析）

Multicentricity of Non-palpable Breast Cancer:A Clinicopathological Study

对１５例无肿块型乳腺癌进行临床及病理分析。这种乳腺癌术前绝大多数被诊断为乳腺增生。其临床特点表现为患者年轻；乳腺触诊无明确肿块，仅表现为区段乳腺增厚；个别病例有乳头溢液，乳腺Ｘ线片可发现腺体内有散在泥沙样钙化，但无肿块影；针吸细胞学检查阳性率低；冰冻切片检查有时也难以作出判断。病理特点主要是癌灶为多灶性的浸润性导管癌；癌灶小，分布广，但只局限在乳腺某一区段内；病变区的腺体都有增生背景。这种类型乳腺癌如能及时发现，预后较好。

Fifteen female patients with non-palpable breast cancer were analyzed clinicopathologically.Of these,a majority were diagnosed as fibrocystic disease(FCD) of the breast preoperatively.The clinical characteristics were younger age of the patients,non-palpable mass in the breast,local thickness of the breast tissue and occasional nipple discharge.The demonstration of irregular distribution of microcalcifications but without visible mass may be found in the mammogram. Fine needle aspiration biopsy and frozen section were not infrequently difficult to establish ocrrect diagnosis. The Pathological finding was multifocal minimal cancerous lesions distributed diffusely within a segment of breast and usually with a FCD background.This type of breast cancer as a rule,usually carries a better prognosis if detected early and properly treate.