摘要
目的:评价茶油的急性毒性和遗传毒性作用。方法:小鼠急性毒性试验、Ames试验,小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验。结果:受试茶油雌、雄小鼠经口LD50均大于20mL/kgBW,属无毒物质;Ames试验、微核试验和精子畸形试验结果均为阴性。结论:在本次实验条件下,受试茶油为无毒物质,未显示有遗传毒性作用。
Objective： To evaluate the genetic toxicity of tea oil. Methods： Acute oral toxicity test in mice, Ames test,micronucleus test of bone marrow PCE cell and sperm abnormality test in mice were used. Results： LD50 of tea oil is more than 20 mL/kgBW by the acute toxicity. The results of genetic toxicity tests are all negative,including Ames test,micronucleus test and sperm adnormality test. Conclusion： Tea oil was considered a substance with no toxicity and mutagenic activity.
出处
《北京联合大学学报》
CAS
2005年第3期66-68,共3页
Journal of Beijing Union University
关键词
茶油
急性毒性试验
遗传毒性试验
tea oil
acute toxicity test
genetic toxicity test
