恶性肿瘤患者780例医院感染的调查与分析

Survey and analysis of infection in hospital for 780 malignancy cases

目的:分析了解恶性肿瘤医院感染的发病情况,找出医院感染相关因素,为临床防治提供依据.方法:对2001年9月～2002年9月住院的恶性肿瘤患者按统一设计的调查项目进行调查,分析总结.结果:恶性肿瘤患者医院感染率为8.5%,明显高于同期其他住院患者的感染率3.83%,P＜0.001;感染部位以上呼吸道(39.39%)为主,其次为下呼吸道(30.30%),胃肠道(18.18%),泌尿道(4.55%);感染率随年龄增高而增加,随住院时间延长而延长;医院感染患者中共检出细菌35株,其中革兰氏阴性菌占57.20%,革兰氏阳性菌占17.1%,真菌占25.71%.结论:医院感染随年龄的增长,住院周期的延长而增加.放、化疗综合者其感染率显著高于单一治疗,两者间差异有统计学意义,P＜0.001.

OBJECTIVE： To analyse the outbread of hospital infection in malignant patients and find the related factors of hospital infection in order to provide the basis for the clinical prevention and treatment. METHODS：Patients with malignant tumors from 2001.9 to 2002.9 were investigated, analysed and summed up by the unified survey items. RESULTS：The hospital infection rate in the malignancy was 8. 5% higher than that in other patients at the same time P〈0. 001 ; the most infection sites were upper respiratioy tract （39.39%）, lower respiratory tract （30.30%）, gastroenteric tract （18. 18%） and urinary tract （4. 55%）. The hospital infection rate was increased following the age and hospitalization period extended. Thirty -five pathogens were checked up. Among them, gram negative bacteria was most （57.20%）, then gram positive （ 17. 1 % ）, the fungi（25. 71 % ） in turn. CONCLUSIONS：The hospital ifection increased following age augmented and hospitalization period extended. The infection rate in radiotherapy colligated with chemotherapeutics was higher than single therapy observably. There was obviously statistcal signaficance. Between them, P〈0. 001.