摘要
本研究通过抑制ACE活性实验,筛选出能发酵脱脂牛乳产生较强抗ACE活性的LacobacillushelveticusATCC15019、15009和LactobacillusthermophilusATCC14485三种乳酸菌菌株,用这三种菌株混合制作的发酵乳对ACE的活性具有较强的抑制作用。分别给原发性高血压大鼠连续三天灌胃此发酵乳和其乳清,结果发现它们都具有较强的降高血压作用,最大降压值分别为24.10±2.69mmHg和29.14±3.07mmHg,与对照组相比,呈极显著性差异(p<0.01)。
The angiotensin-I-converting enzyme （ACE） inhibitory activity of f yogurt fermented with four lactic acid bacteria was investigated. The results found that the yogurt fermented with L. helveticus ATCC15019, 15009 and L. thermophilus ATCC 14485 had the potent inhibitory activity on ACE. After the oral administration of the yogurt or its whey to spontaneously hypertensive rats （SHR） for three days, results showed that both of them had the antihypertensive effect, with the most decrease value of 24.10 ±2.69mmHg and 29.14 ± 3.07mmHg of systolic blood pressure（SBP）, which showed outstanding differences, compared with the control groups.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2005年第9期446-450,共5页
Food Science
基金
国家十五奶业重大科技专项(2002BA518A12)
江苏省十五攻关项目(BE2002302)
江苏省自然科学基金(BK2005137)
关键词
发酵乳
ACE
抗高血压
fermented milk （Yogurt）
angiotensin-I-converting enzyme （ACE）
antihypertensive
