外周T细胞性淋巴瘤22例病理临床及免疫组化观察

PERIPHERAL T-CELL LYMPHOMAS: A CLINICO PATHOLOGICAL AND IMMUNOLOGICAL ANALYSIS OF 22 CASES

T细胞性淋巴瘤在我国约占非何杰金淋巴瘤(NHL)的24.3％～29％。该类肿瘤有多种组织形态及临床表现,至今对T淋巴母细胞性淋巴瘤、蕈样肉芽肿、Sezary氏综合症的病理临床特征已有较全面的认识,而对外周T-NHL的认识尚很不足,在诊断及分类分型上均有不少困难,现将22例外周T-

Twenty two cases of primary peripheral T-cell lymphoma from lymph nodes werereported. Ristological types were: small lymphocytic 1 case, uniform medium-sized cell4, Lennert's lymphoma 1,immunoblastic 1,clear round nuclear cell 2, AILD-like 5 andpolymorphic 8. Immunological phenotypes were: T-helper 21 cases and T-suppressor1 case.No definite correlation could be found between the immunotype and the morpho-logical type. 17 cases were over 30 years of age. Male-femal ratio was 2.1:1. Thefollow-up data of 15 cases showed that 10 are still liVing (8-60 months) and 5 died withtumor(4-14 months). It is difficult to show certain correlation between morphologicaltypes and prognosis. The major morphological characteristics and differential diagnosisfor each type were diseussed.