α-羰基环十二酮的酮-烯醇互变异构中的构象效应

Conformational Effect on the Keto-enol Tautomerism of α-Carbonylcyclododecanones

利用1H NMR技术研究了α-羰基环十二酮的酮-烯醇互变异构.结果表明,取代基、温度和溶剂对互变异构的影响与已知的规律一致,但是烯醇的含量与相应的α-羰基环己酮相比要低得多,利用构象效应对其进行了合理的解释.

The keto-enol tautomerism of α-carbonylcyclododecanones has been studied by means of ^1H NMR technology. The result shows that the effects of substituent, temperature and solvent on the tautomerism agreed with the known rules, while their enol contents were much lower than those of the corresponding a-carbonylcyclohexanones, which is illustrated reasonably by the conformational effect.