微波辐射下一步合成9-芳基-1,2,3,4,5,6,7,8,9,10-十氢-1,8-吖啶二酮被引量：4

One-pot Synthesis of 9-Aryl-1,2,3,4,5,6,7,8,9,10-decahydro- 1,8-acridinedione under Microwave Irradiation

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摘要以芳醛、1,3-环己二酮、醋酸铵为原料在无溶剂条件下经微波辐射合成了一系列9-芳基-1,2,3,4,5,6,7,8,9,10-十氢-1,8-吖啶二酮.该反应的反应时间短、产率高、环境友好、后处理方便.产物的结构经红外光谱、核磁共振谱表征,3d的结构经单晶X射线衍射进一步确证. A series of 9-aryl-1,2,3,4,5,6,7,8,9,10-decahydro-1,8-acridinedione derivatives were synthesized via the reaction of aromatic aldehydes with 1,3-cyclohexanedione and ammonium acetate in solvent-free conditions under microwave irradiation by one-pot reaction. The reaction easily could be worked up with short reaction time, high yields and environmental friendliness. The structures of the products were confinned by IR and ^1H NMR spectra. The structure of 3d was further determined by X-ray analysis.

作者华国平李团结邹翔屠树江朱松磊章晓镜纪顺俊张勇

机构地区徐州建筑职业技术学院徐州师范大学化学系江苏省药用植物生物技术重点实验室苏州大学化学化工学院

出处《有机化学》 SCIE CAS CSCD 北大核心 2005年第10期1294-1297,共4页 Chinese Journal of Organic Chemistry

基金国家自然科学基金(No.20372057) 江苏省自然科学基金(No.BK2001142) 江苏省苏州大学化学化工学院有机合成重点实验室开放基金(No.S8109111) 江苏省药用植物生物技术重点实验室开放基金(No.01AXL14)资助项目.

关键词芳醛 1 3-环己二酮吖啶二酮微波辐射微波辐射合成环己二酮一步合成芳基吖啶单晶X射线衍射 aromatic aldehyde 1,3-cyclohexanedione microwave irradiation acridinedione

分类号 O626.2 [理学—有机化学]

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