摘要
以芳醛、1,3-环己二酮、醋酸铵为原料在无溶剂条件下经微波辐射合成了一系列9-芳基-1,2,3,4,5,6,7,8,9,10-十氢-1,8-吖啶二酮.该反应的反应时间短、产率高、环境友好、后处理方便.产物的结构经红外光谱、核磁共振谱表征,3d的结构经单晶X射线衍射进一步确证.
A series of 9-aryl-1,2,3,4,5,6,7,8,9,10-decahydro-1,8-acridinedione derivatives were synthesized via the reaction of aromatic aldehydes with 1,3-cyclohexanedione and ammonium acetate in solvent-free conditions under microwave irradiation by one-pot reaction. The reaction easily could be worked up with short reaction time, high yields and environmental friendliness. The structures of the products were confinned by IR and ^1H NMR spectra. The structure of 3d was further determined by X-ray analysis.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2005年第10期1294-1297,共4页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(No.20372057)
江苏省自然科学基金(No.BK2001142)
江苏省苏州大学化学化工学院有机合成重点实验室开放基金(No.S8109111)
江苏省药用植物生物技术重点实验室开放基金(No.01AXL14)资助项目.