摘要
最近研究表明,白细胞介素2（IL-2）在体外能够诱导产生被淋巴因子激活的杀伤细胞（LAK）,在适当IL-2存在条件下,这些LAK细胞能对肿瘤细胞产生强大的杀伤作用。然而IL-2附加LAK细胞治疗方案毒副作用太大,不宜用于临床。
Comprehensive immunotherapy (lymphokine mixture) or immunochemotherapy(lymphokine mixture + 5-FU) were given to 127 patients with hepatocellular carcinoma.The result indicated that NK,ADCC activity and lymphocyte transformation ratewere significantly improved in vivo after treatment. The NK activity in cancer tissuewas deeply suppressed, but could be recovered to normal leyel after being treated withlymphokine mixture and 5-FU as demonstrated by in vitro assay. In the patients who re-ceived postoperative comprehensive immunotherapy, the recovery rate of immunity waskigher and tumor recurrent rate was significantly decreased. The survival rate in caseswith unresectable tumor was also prolonged.
出处
《肿瘤》
CAS
CSCD
北大核心
1989年第3期100-101,共2页
Tumor
