拟南芥及水稻转录因子MADS密码子的偏好性比较

Comparison of MADS transcriptional factor on codon bias in arabidopsis and rice

大多数与花发育相关的功能基因属于MADS基因家族.应用CodonW的因子分析表明,拟南芥MADS转录因子家族偏好使用A、U结尾的密码子,而水稻MADS转录因子家族偏好使用G、C结尾的密码子.同时通过氨基酸序列的多重比对,表明密码子偏好性与氨基酸序列及二级结构之间存在关联,证实了不同的密码子编码的氨基酸位于蛋白质二级结构的特定位置.

Most of the flower development-related functional genes are belong to MADS transcription factors families. Through the factorial correspondence analysis（FCA） of CodonW, we can find out that MADS transcriptional factors in Arabidopsis prefer to A-ending and U-ending codons, while that in rice prefer to G-ending and C-ending codons. By using the ClustalX for searching the relation between the bias of the codons and second structure of the MADS, we confirm that the amino acids coding by different codons are on the special position of the second structure of the proteins.