尼群地平与氨酰心安单用及合用治疗高血压病的降压效果和对左心功能影响的比较

Comparison of nitrendiping,atenolol and their combination in the treatment of hypertension.

高血压病Ⅰ、Ⅱ期９０例分为三组，对尼群地平２０ｍｇ、氨酰心安５０ｍｇ单用及合用而剂量减半的降压效果和左心功能影响进行了比较。结果表明两药合用副作用减少，降压效果不变，对左室收缩和舒张功能改善更加全面。

The study included 90 hypertensive patients.They were divided into three groups.The antihypertensive efficacy of nitrendipine(20mg),Atenolol (50mg) alone was compared to their combination(nitrendipine 10mg plus atenolol 25mg).comparative effects of the these drugs on left ventricular systolic and diastolic function parameters were assessed by pulsed doppler echocardiography.In conclusion,The therapy of half dose nitrendipine-atenolol combination was effective in lowering blood pressure.The left ventricular function was improved and the adverse effects were counteracted.