直立百部的化学成分

Chemical Constituents of Stemona sessilifolia

目的:研究直立百部Stemona sessilifolia(Miq.) Miq.根中的化学成分.方法:运用各种色谱方法进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构.结果:从直立百部中分离得到9个化合物,分别鉴定为Protostemotinine (1)、Stemospironine (2)、Stilbostemin B (3)、Stilbostemin D (4)、4'-Methylpinosylvin(5)、芝麻素(6)、28-羟基-正二十八烷酸-3'-甘油单酯(7)、26-羟基-正二十六烷酸-3'-甘油单酯(8)及β-谷甾醇(9).结论:化合物2～8为首次从该植物中分离得到.

AIM：To study the chemical constituents of roots of Stemona sessilifolia （Miq.）Miq.. METHODS： The constituents were isolated and purified by the column chromatography. Their structures were identified according to their physical and chemical properties as well as spectral data. RESULTS ： Nine compounds were isolated from roots of Stemona sessilifolia, and their structures were elucidated as protostemotinine （ 1 ）, stemospironine （2）, stilbostemin B （3, 5-dihydroxy-4-methylbi-benzyl ） （ 3 ）, stilbostemin D （ 3, 5-dihydroxy-2＇-methoxy-4-methyl-bibenzyl ） （ 4 ）, 4＇- methylpinosylvin（4-methyl-3,5-dihydroxystilbene） （5）, sesamin（6）, 28-hydroxy-octacosanic acid-3＇-glycerinmonoester （7）, 26- hydroxy- hexacosanic acid-3＇-glycerin-monoester（8） and 13-sitosterol （9）. CONCLUSION ： Compounds 2 - 8 were isolated from Stemona sessilifolia （Miq.）Miq. for the first time.