视网膜色素变性的相干光断层成像

Retinitis pigmentosa′ characteristics for optical coherence tomography

目的通过相干光断层成像(optical coherence tomography,OCT)观察原发性视网膜色素变性(retinitis pigmentosa,RP)患者的视网膜黄斑区图像特征。方法对临床诊断为原发性视网膜色素变性的25例50只眼进行相干光断层成像检查,观察形态特点并进行厚度测量。结果原发性视网膜色素变性患者黄斑区的相干光断层图像,通常有6种表现:1.神经上皮层弥漫性增厚即水肿(厚度>170μm),13只眼(26%)。2.黄斑囊样水肿8只眼(16.7%)。3.神经上皮层萎缩薄变(<120μm),18只眼(36%)。4.视网膜色素上皮层和脉络膜毛细血管层萎缩薄变,见于所有患者。5.黄斑前膜4只眼(8%)。6.黄斑正常厚度。结论相干光断层成像有助于较早地发现RP的各种黄斑病变,是很有用的检查方法。

Objective To observe the characteristic of macular in patients with retinitis pigmentosa （RP） by optical coherence tomography （OCT）. Methods Twenty - five patients of RP were examined to measure the thickess of macular by OCT. Results CKT images of macular in patients with retinitis pigrnentcxsa （RP） have six kinds of expressions： l.the edema of the neurosensory retina （thickness 〉 170μm）, 13eyes （26%）. 2. cystoid macular edema, eight eyes （ 16% ）. 3. the thinning of the neurosensory retina （ thickness〈 120μm）, right eyes （ 16% ）. 4. retinal pigment epithelium and choroidal capillary vessel are observed in all patients. 5. epiretinal membrane, four eyes （8%）. 6. normal thickness of macular. Conclusions OCT is eligible to find the chancre of macular in RP patients. It is a useful tool for doctors in clinic work.