小儿感染与多系统器官功能衰竭（附12例临床及病理分析）

Postoperative Radiotherapy of Seminoma (Clinical Analysis of 62 Cases)

本文对１２例小儿感染致多系统器官功能衰竭死亡病例进行临床及病理分析。临床表现有发热、外周血白细胞总数增高、心率增快、呼吸困难、呕吐、意识障碍、无尿等。病理学检查见多器官组织内炎细胞浸润；脏器充血、水肿、出血、ＤＩＣ形成；组织细胞变性、坏死；淋巴器官增生、坏死等病变。其中发生二器官功能衰竭３例，三器官功能衰竭３例，四器官功能衰竭６例。本文在形态学上进一步证实了多系统器官功能衰竭发生的炎症介质学说、微循环障碍、肠源性感染和免疫机能下降的综合作用机理。

Sixty-two postoperatiue patients with seminoma in Oct. 1977 to Dec. 1985, were treated by radiotherapy. All patients were detected by pathological examination and followed up more than 5 years. The 5 and 8 years survival rate were 85.6% (53/62) and 73.3% (33/45) respetively. The doses of 35 to 45 GY/3.5 to4.5 WK were considered to be optimal to control this disease.Analysis of prognostic factors has shown that the 5 year survival rate has no relationship with the suffering age, but has close relationship with the staging. In order to promote the long term treat effect of the patients with higher than Ⅱ stage, radiotherapy follows by chemotherapy is more important.