肺癌患者血清糖类抗原153与癌胚抗原的关系探讨

Relationship between levels of serum CA153 and CEA in patients with lung cancer

目的探讨肺癌患者血清糖类抗原153(CA153)水平及其临床意义。方法采用放射免疫分析法检测肺癌患者血清中CA153和癌胚抗原(CEA)的含量,并与正常健康人作比较。结果肺癌患者血清中CA153和CEA水平显著地高于正常人(P<0.01),经手术治疗后3个月与正常人比较差异无显著性(P>0.05)。结论检测肺癌患者血清中CA153、CEA水平对观察病情和预后判断具有重要的临床价值。

Objective To study the levels of serumCA153 in patients with lungcancer and its significance. Methods Levels of serum CA153 and CEA were detected in patients with lung cancer（n=31） and 30 normal controls by radioimmunoassay. Results Levels of serum CA153 and CEA in patients with lung cancer were significantly higher than those in normal controls（P〈0.01）. Three months after operation there was no significance（P〈0.05）. Conclusion The detection of serum CA153 and CEA levels may be of help to judge the severity of the lung diseases and evaluate the patient＇s prognosis and thus may possess an important clinical value.