摘要
用特异性放射免疫分析法测定３０例肝硬变、１５例肝癌和２０例正常人的血浆内皮素含量。结果表明，肝硬变组、肝癌组血浆内皮素水平明显高于正常对照组（Ｐ＜０．０１）。肝硬变组中伴有腹水２０例，不伴腹水１０例，二者血浆内皮素水平接近（Ｐ＞０．０５）。提示在肝硬变、肝癌的发生、发展中内皮囊可能起着重要作用，而对肝硬变腹水的形成并无明显关系。
The plasma levels of endothelin(ET)were determined by radioimmunoassay in 30 patientswith liver cirrhosis,13 patients with liver carcinoma and 20 healthy volunteers. The results re-vealed that mean ET plasma level was significantly higher in cirrhosis group and liver carcinomagroup than that in control group.The results sugget that ET might be one of the important fac-tors involved in the occurrence and development of cirrhosis and liver carcinoma.
出处
《湖南医科大学学报》
CSCD
1996年第2期129-130,共2页
Bulletin of Hunan Medical University
关键词
内皮素
肝硬化
肝肿瘤
endothelin
liver cirrhosis
liver carcinoma
ascites
