烧伤休克合并脑水肿患儿100例治疗分析

The analysis in 100 cases of burn shock with cerebral edema

目的观察烧伤休克合并脑水肿患儿不同治疗方法的疗效。方法100例烧伤休克合并脑水肿患儿按烧伤程度、烧伤面积等分为纳洛酮治疗组和对照组,比较两组临床疗效。结果两组治疗后临床各项指标较治疗前均有不同程度的改善,治疗组改善程度优于对照组(P<0.05～0.01);无论治疗组和对照组肿瘤坏死因子(TNF)含量均明显高于正常对照组(P<0.01),治疗后低于治疗前(P<0.05);治疗组疗效高于对照组(P<0.05)。结论应用纳洛酮治疗烧伤休克合并脑水肿有较好的疗效。

Objective To observate curative effect of burn shock with cerebral edema by different treatment method. Methods 100 examples burnses shock with cerebral edema according to the degree,and suffer burns area, were divided into the naloxone teatment group and the normal control group,and two group clinical curative effect were compared. Results Clinical index hed improvemented in two groups,but is of treatment group was higher than that of control group（ P 〈 0.05～ 0.01 ） ;the contens of tumour necrosis factor（TNF） was obviously higher than normal control group（ P 〈 0.01 ） ; the contens of TNF after treatment was lower than that before treatment（ P 〈 0.05 ） ; the curative effect of treatmen group was higher than that of control group （P 〈 0.05）. Conclusion The curative effect of naloxone can get the better for the patients in burn shock with cerebral edema.