2型糖尿病合并急性心肌梗死临床分析

Clinical research of type 2 diabetes with acute myocardial infarction

目的探讨2型糖尿病(T2DM)合并急性心肌梗死(AMI)患者的冠脉病变及临床特点。方法对339例经冠脉造影确诊为冠状动脉粥样硬化病变的AMI患者分为T2DM合并AMI组(78例)和AMI组(261例),进行冠脉病变程度和临床表现比较。结果T2DM合并AMI组冠脉三支病变、重度狭窄、弥漫性病变多于AMI组(P<0.01),严重心律失常、心力衰竭、心源性休克、住院死亡率也高于AMI组(P<0.01或<0.05)。结论T2DM合并AMI患者冠脉病变和临床表现较无T2DM的AMI患者重,病死率高。

Objective To study clinical feature and coronary artery lesion characteristics of type 2 diabetes （T2DM） with acute myocardial infarction（AMI）. Methods The coronary angiography（CAG） was undergone in 78 patients of T2DM with AMI（group A） and 261 patients of AMI without type 2 diabetes. Results The angiography characters between the two groups were significantly different. Triple vessel lesion, the diffuse vascular lesion and severe stenosis of group A were significantly severer than those of group B（P〈 0.05 ）. The morbidity of severe arrhythmias, heart failure,cardial shock and mortality of A group were higher than those of B group（P〈 0.01 or 〈 0. 05）. Conclusion The coronary arterial stenosis and the clinical features of T2DM with AMI are worse than those of AMI without T2DM,and mortality is increased.