期刊文献+

消化性溃疡、慢性胃炎患者幽门螺杆菌产毒株抗体检测分析 被引量:7

原文传递
导出
摘要 目的研究消化性溃疡、慢性胃炎与幽门螺杆菌产毒株之间的关系。方法用定性酶联免疫检测法测定患者血清幽门螺杆菌总抗体和产毒株抗体,并行统计学分析。结果胃溃疡(DU)、十二指肠溃疡(GU)、胃炎组检测HpAb阳性结果差异有显著意义(P<0.05),DU感染Hp率较高;已被Hp感染的DU、GU、胃炎组细胞毒素相关蛋白(CagA)抗体阳性结果差异无显著意义(P>0.05)。结论幽门螺杆菌与消化性溃疡、慢性胃炎等疾病的发生密切相关。CagA阳性Hp菌株感染是引起上述疾病的一个非常重要的因素。测定产毒株Hp抗体,在Hp感染相关特定性疾病诊断中有一定的临床意义。
出处 《中国基层医药》 CAS 2005年第9期1238-1238,共1页 Chinese Journal of Primary Medicine and Pharmacy
  • 相关文献

参考文献5

二级参考文献15

  • 1Rauws EAJ, Tytgat GNJ. Cures duodenal ulcer associated with eradication of Helicobacter pylori [ J ]. Lancet, 1990, 335 ( 8700 ):1233 - 1235.
  • 2Arakawa T, Higuchi K, Nebiki H, et al. Morphological and functional maturity of healed gastric ulcer: association with ulcer relapse [ J]. Japan J Digestive association, 1992, (Suppl): 1960.
  • 3Tarnawski A, Stachura J, William JK, et al. Quality of gastric ulcer healing: a new emerging concept [ J]. J Clin Gastroenterrol, 1991,13 (1): 42.
  • 4Pan S, Liao CH. The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2 - antagonist [J]. Am J Gastroenterol, 1990, 85 (8): 949-952.
  • 5Sarosiek J, Marshall BJ, Peura DA. Gastroduodenal mucus gel thickness in patients with Helicobacter pylori: A method for assessment of biopsy specimens [J]. Am J Gastroentrol, 1991, 86 (6): 729 -734
  • 6Shirotani T, Okada M, Murayama H, et al. Effect of the eradication of Helicobacter pylori on duodenal ulcer healing and ulcer relapse: randomized controlled study in Japan [ J ] . J Gastroenterology, 1996, 31(2): 175-181.
  • 7Arkkila PE, Seppala K, Kosunen TU, et al. Eradication of Helicobacter pylori improves the healing rate and reduces the relapse rate of nonbleeding ulcers in patients with bleeding peptic ulcer [ J ]. Am J Gastroenterol, 2003, 98 (10): 2149-2156.
  • 8Pan S, Liao CH, Lien GS, et al. Histological maturity of healed duodenal ulcer and ulcer recurrence after treatment with colloidal bismuth subcitrate or cimetidine [ J ]. Gastroenterology, 1991 , 101 ( 5 ):1187 -1191.
  • 9Ricci V, Ciacci C, Zarrilli R et al. Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro: role of vacA and cagA [J]. Infect Immun, 1996, 64 (7): 2829-2833.
  • 10Fan X G,Gut,1996年,38卷,19页

共引文献48

同被引文献37

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部