肝硬化并发上消化道出血的危险因素分析

Risk factors of upper gastrointestinal bleeding of hepatic cirrhosis complication

目的了解肝硬化并发上消化道出血的相关危险因素,为预防和控制疾病提供可靠依据。方法将130例肝硬化患者分为出血组64例,非出血组66例。采用单、多因素分析法对肝硬化上消化道出血的相关因素进行分析并进行病例对照研究。结果肝硬化并发上消化道出血与食管静脉曲张(OR=3942,P=0.001)、肝功能分极(OR=1.028,P<0.05)、门脉高压性胃病(OR=3.862,P<0.05)显著相关。结论肝硬化并发上消化道出血的危险因素是食管静脉曲张、肝功能分极、门静脉内径、门脉高压性胃病。

Objective To analyse risk factors of upper gastrointestinal bleeding in hepatic cirrhosis, in order to provide reliable basis for prevent and control bleeding. Methods One hundred and thirty cirrhotic patients were studied with single and multiple factors analysis. Results Upper gastrointestinal bleeding of cirrhosis has noticeably connections with esophagus bleeding （ OR = 3. 942, P = 0.001）, liver function grade （ OR = 1.028, P = 0.003）, portal hypertensive gastric mucosal lesion （ OR = 3. 862, P = 0.002）. Conclusion Risk factors of upper gastrointestinal bleeding of cirrhosis are esophagus venous bleeding, liver function grade, and respectively.