高原地区798名健康人静脉血细胞参数参考值分析及意义

ANALYSIS TAHE REFERENCE VALUE OF VENOUS BLOOD IN 798 ADULTS AT HIGH ALTITUDE AND ITS SIGNIFICANCE

目的确定高原地区(3225m)健康成人静脉血细胞常用指标参考值的范围。方法用日本SysmexSF-3000血液分析仪检测高原地区健康成人静脉血细胞参数,并以《诊断学》(人民卫生出版社)公布的正常值为对照。结果高原地区WBC、N#参考值上下限均低于《诊断学》;N%参考值下限略下移,M%参考值上下限略高,E#参考值上下限略低,而B%和B#参考值相近。Hb参考值女性和男性上下限值均上移,PLT参考值为(70-218)×109/L,其上下限值显著低于《诊断学》。MPV和PDW上下限与北京协作组参考值相比呈显著增高,女性Hct、RBc值同北京市协作组血液分析调查值接近,而男性Hct,RBC值比北京市协作组调查的值及《诊断学》等教科书中的参考值高。其余指标与《诊断学》参考值相比无差异。结论高原地区静脉血三大血系部分指标与《诊断学》参考值相比有明显差异,可作为初步确定高原地区健康成人静脉血常用指标的参考值。

Objective To establish the reference value of venous blood of 798 adults at altitude of 3225m. Methods 798 health adults＇ venous blood were taken and the related reference values were determined by Sysmex SF-3000 hematoanalyzer, and the results were analyzed by comparing with sea-level residents＇ data. Results Comparing with plain values, the upper and lower values of WBC of healthy adults at altitude of 3225m are markedly decrease, reference values of N%, N#,E% and E# are lower , but reference values of L% ,L#,N#, M% ,M# are higher; The average level of PLT at altitude of 3225m is obviously lower than at plain,Upper and lower limits values of MPV and PDW are higher than at plain; The Hb,Hct, RBC average level at altitude of 3225m have remarkably increases than one at plain. Conclusion There is remarkably difference on average level of some venous blood parameters between high altitude and plain residents. The results of this investigation will set up the basic data bank for reference ranges of venous blood of healthy people at plateau.