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影响非何杰金淋巴瘤化疗效果的因素分析 被引量:2

CLINICAL FEATURES AND PROGNOSTIC FACTORS OF NON-HONGKINS LYMPHOMA ANALYSIS OF 108 CASES
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摘要 本文分析非何杰金氏淋巴瘤(NHL)108例,其中低度恶性10例,中度恶性60例,高度恶性28例,分度不明10例。首发于浅表淋巴结者共66例(61.1%),受侵部位以颈淋巴结区居多,共45例(41.7%)。全组化疗总缓解率为71%,其中COPP,CHOP,BACOP及EPCOP四组方案缓解率的差异无显著性。而高、中、低度恶性组缓解率的差异有高度显著性,恶性程度越高,缓解率越高。四组方案的主要毒副作用为骨髓抑制。 cases of Non-Hongkins Lymphoma(NHL)including 10 cases of low grade malignancy,60 cases of intermediate grade,28 cases of high grade and 10 cases of unknown grade were analysed.En- larged superficial lymphnodes were observed as the first sites of invasion in 66 cases (61.2%).The most fre- quent sites of invasion were cervical regions(41.7%).Total remission rate(RR)of chemotherapy was71%. The differences of RR for various regimens CHOP,COPP,BACOP,and EPCOP were not signifi- cant.But the RR in groups of low,intermediate and high grade lymphoma were different significantly(P<0.005).The higher the grade the higher the remmission rate,Myelosuppression was the main side effectfor all four protocols.
机构地区 四川省肿瘤医院
出处 《癌症》 SCIE CAS CSCD 北大核心 1996年第3期208-210,共3页 Chinese Journal of Cancer
关键词 淋巴瘤 NHL 药物疗法 疗效 Non-Hongkins Lymphoma Grade of Malignancy Drug Therapy
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参考文献2

  • 1孙燕,临床肿瘤内科手册.2,1991年
  • 2孙燕,肿瘤药物治疗,1987年

同被引文献5

  • 1孙燕 周际昌.临床肿瘤内科手册[M](第3版)[M].北京:人民卫生出版社,1997.45.
  • 2MILLER AB, HOOGSTRATEN FB, STAQUET M, et al. Reporting results of cancertreatment[J]. Cancer, 1981, 47: 207.
  • 3孙燕.恶性淋巴瘤[A].见:王肇炎,韩锐主编.肿瘤药物治疗[M].北京:人民卫生出版社,1987.144~170.
  • 4冯奉仪.头颈部恶性淋巴瘤[A].见:王奇璐主编.恶性淋巴瘤的诊断与治疗[M].北京:北京医科大学中国协和医科大学联合出版社,1997.308~312.
  • 5孙燕,周际昌.临床肿瘤内科手册[M]人民卫生出版社,1996.

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