摘要
本文分析非何杰金氏淋巴瘤(NHL)108例,其中低度恶性10例,中度恶性60例,高度恶性28例,分度不明10例。首发于浅表淋巴结者共66例(61.1%),受侵部位以颈淋巴结区居多,共45例(41.7%)。全组化疗总缓解率为71%,其中COPP,CHOP,BACOP及EPCOP四组方案缓解率的差异无显著性。而高、中、低度恶性组缓解率的差异有高度显著性,恶性程度越高,缓解率越高。四组方案的主要毒副作用为骨髓抑制。
cases of Non-Hongkins Lymphoma(NHL)including 10 cases of low grade malignancy,60 cases of intermediate grade,28 cases of high grade and 10 cases of unknown grade were analysed.En- larged superficial lymphnodes were observed as the first sites of invasion in 66 cases (61.2%).The most fre- quent sites of invasion were cervical regions(41.7%).Total remission rate(RR)of chemotherapy was71%. The differences of RR for various regimens CHOP,COPP,BACOP,and EPCOP were not signifi- cant.But the RR in groups of low,intermediate and high grade lymphoma were different significantly(P<0.005).The higher the grade the higher the remmission rate,Myelosuppression was the main side effectfor all four protocols.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1996年第3期208-210,共3页
Chinese Journal of Cancer
关键词
淋巴瘤
NHL
药物疗法
疗效
Non-Hongkins Lymphoma Grade of Malignancy Drug Therapy