期刊文献+

抗体酶技术在医学上的应用

The Applications of Abzyme in Medicine
下载PDF
导出
摘要 抗体酶是一类可变区被赋予了酶催化活性的抗体分子,可以催化许多天然酶无法催化的化学反应,在医学、工业、农业等众多领域具有广泛的应用前景和潜在的应用价值。该文介绍抗体酶及其制备策略和方法;抗体酶技术在医学领域的应用及研究进展。
作者 王欣 王继红
出处 《生命的化学》 CAS CSCD 北大核心 2005年第5期396-399,共4页 Chemistry of Life
基金 重庆医科大学校办基金(No.XB200328)
关键词 抗体酶 应用
  • 相关文献

参考文献2

二级参考文献15

  • 1[1]Doroshow J H.Glutathione peroxidase and oxidative stress [J].Toxicol Lett,1995,82/83:395-398.
  • 2[2]Arai M,Imai H,Koumura T,et al.Mitochondrial phospholipid hydroperoxide glutathione peroxidase plays a major role in preventing oxidative injury to cells [J].J Biol Chem,1999,274(8):4924-4933.
  • 3[3]Sies H.Ebselen,a selenoorganic compound as glutathione peroxidase mimic [J].Free Radical Biol Med,1993,14(3):313-323.
  • 4[4]Sies H.Ebselen:a glutathione peroxidase mimic [J].Methods Enzymol,1994,234:476-482.
  • 5[5]Sies H,Masumoto H.Ebselen as a glutathione peroxidase mimic and as a scavenger of peroxynitrite [J].Adv Pharmacol,1997,38:229-246.
  • 6[6]Sies H,Arteel G E.Interaction of peroxynitrite with selenoproteins and glutathione peroxidase mimics [J].Free Radical Biol Med,2000,15(10):1451-1455.
  • 7[7]Ren X J,Gao S J,You D L,et al.Cloning and expression of a single-chain catalytic antibody that acts as a glutathione peroxidase mimic with high catalytic efficiency [J].Biochem J,2001,359:369-374.
  • 8[8]Wilson S R,Zucker P A,Hung R C,et al.Development of synthetic compounds with glutathione peroxidase activity [J].J Am Chem Soc,1989,111:5936-5939.
  • 9[9]Cordis G A,Maulik N,Das D K.Detection of oxidative stress in heart by estimating the dinitrophenylhydrazine derivative of malonaldehyde [J].J Mol Cell Cardiol,1995,27(8):1645-1653.
  • 10[10]Gerlier D,Thomasset N.Use of MTT colorimetric assay to measure cell activation [J].J Immunol Methods,1986,94(1-2):57-63.

共引文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部