辐射法制备壳聚糖/聚丙烯酸水凝胶及其溶胀性能研究

Preparation of CS/PAAc copolymer hydrogel with irradiation method and characterization of its swelling properties

采用电子束对壳聚糖和丙烯酸混合水溶液进行辐照,制得了壳聚糖/聚丙烯酸(CS/PAAc)共聚物水凝胶。研究了pH值、各组分配比和辐照剂量等因素对产物溶胀率的影响。结果表明,水凝胶具有pH敏感性,在强酸性(pH≈1)和碱性(pH>7)条件下均表现出较好的溶胀性;而在pH2—5范围内溶胀率较小。同时,随着辐照剂量的增大,产物的溶胀率也随之增大,在酸性条件下表现并不明显,而当pH>6时增大效果较显著。

Chitosan/poly（acrylic acid） （CS/PAAc） copolymer hydrogel was prepared by E-beam irradiation of mixed aqueous solution of chitosan and acrylic acid. The effect of pH, composition and irradiation dose on the equilibrated swelling ratio of the hydrogels was determined. Experimental results show that the hydrogels swelled well in both lower pH （pH≈1） and higher pH （pH〉6）, however, they shrunk in the range of pH 2-5.