大青叶化学成分研究

Studies on chemical constituents in leaf of Isatis indigotica

目的:研究大青叶乙醇总提取物中的化学成分。方法:应用各种柱色谱方法对其提取物进行化学成分分离,并应用化学方法和现代波谱分析方法鉴定所分离得到的化学成分。结果:从大青叶乙醇总提取物中分离得到3个化合物,经鉴定为吲哚类化合物靛玉红(indirubin)、喹唑酮类化合物色胺酮(tryptanthrin)及焦谷氨酸(L-py-roglutamic acid)。结论:焦谷氨酸为首次从菘蓝属植物中分离得到,色胺酮系从该植物叶中首次分离得到。

Objective： To study the chemical constituents of the leaf of Isatis indigotica. Method： Chromatography and spectral analysis were respectively used to isolate and identify the constituents. Result： Three compounds were isolated from the ethanol extracts of the leaf of I. indigotica, and identified as indirubin, tryptanthrin and L-pyroglutamie acid. Conclusion： L-pyroglutamic acid was isolated from the genus for the first time, and tryptanthrin was isolated from the leaf of this plant for the first time.