一种隐形眼镜护理液杀灭微生物效果的试验观察

EXPERIMENTAL OBSERVATION ON GERMICIDAL EFFICACY OF A MULTI-FUNCTIONAL SOLUTION FOR CONTACT LENS

一种隐形眼镜护理液主要杀菌成分为聚六亚甲基胍。采用悬液定量杀菌试验对该护理液杀灭细菌繁殖体和酵母菌的效果进行了实验室观察,以便了解其消毒效果。结果,以该护理液原液对大肠杆菌、金黄色葡萄球菌和绿脓杆菌作用3 h,杀灭率均达到100%;对白色念珠菌作用6 h,杀灭率为97.60%。体积分数10%小牛血清对其杀菌效果无明显影响。用该护理液原液浸泡隐形眼镜新镜片6 h,对镜片上金黄色葡萄球菌平均消除率为99.92%,对白色念珠菌平均消除率为99.45%。结论,该护理液原液对细菌繁殖体和酵母菌具有很好的杀灭效果,性能稳定。

The main germicidal ingredient of multi - functional solution for contact lens is polyhexamethylene guanidine. Suspension quantitative germicidal test was used to carry out laboratory observation on efficacy of this solution in killing vegetative forms of bacteria and yeasts in order to know its disinfection efficacy. Results： The killing rates of Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa exposed to the stock solution of this solution for 3 h attained 100%. The killing rate of Candida albicans exposed to the stock solution for 6 h was 97.60%.10% （v/v） calf serum had no significant influence on its germicidal efficacy. Immersion of new contact lens in the stock solution for 6 h eliminated 99.92% in average of Staphylococcus aureus on the lens and 99.45% in average ofCandida albicans. Conclusion： The stock solution of the multi - functional solution for contact lens has good efficacy in killing vegetative forms of bacteria and yeasts and is stable in properties.