期刊文献+

4种抗高血压药物治疗方案的成本-效果分析 被引量:11

Cost-Effectivness Analysis on 4 Treatment Regimens for Hypertension
下载PDF
导出
摘要 目的:评价4种抗高血压药物治疗方案的成本-效果。方法:将212例高血压患者随机分为4组,A组给予氨氯地平,B组给予福辛普利,C组给予坎地沙坦酯,D组给予氯沙坦钾,观察各组疗效,并进行成本-效果分析。结果:C组疗效显著高于A、B、D组(P<0·05),且C组成本-效果比为4组中最低。结论:坎地沙坦酯(C组)方案治疗高血压较佳。 OBJECTIVE: To compare the, costs and effectiveness of 4 treatment regimens for hypertension. METHODS: 212 cases of hypertension were randomly divided into 4 groups,group A treated with amlodipine,group B treated with fosinopril,group C treated with candesartan cilexetil,and group D treated with losartan;the curative effects in each group were observed and cost effectiveness analyses were made, RESULTS: The effective rate in group C was markedly higher than those in other 3 groups(P〈0.05),and the cost - effectiveness ratio in group C was the lowest. CONCLUSION:The regimen of candesartan cilexetil (group C)is the preferable one for hypertension.
出处 《中国药房》 CAS CSCD 北大核心 2005年第20期1553-1555,共3页 China Pharmacy
关键词 高血压 治疗方案 成本-效果分析 Hypertension Treatment regimen Cost-effectiveness analysis
  • 相关文献

参考文献11

  • 1Pamsti G, Pondonsi G, Alloni F, et al.Relationship of 24 hour blood pressure mean and variability to secrecity of target- organ damage in hyperteinsion[J].J Hyper-tene, 2000, 5: 93.
  • 2林曙光,陈鲁原.治疗高血压的药物经济学评价[J].中华心血管病杂志,2003,31(3):236-237. 被引量:40
  • 3刘国仗,胡大一,陶萍,诸骏仁,郭林妮,郭静萱,游凯.心血管药物临床试验评价方法的建议[J].中华心血管病杂志,1998,26(1):5-11. 被引量:1439
  • 4哈娜,哈力,张新建.4种钙剂治疗老年性骨质疏松症的成本-效果分析[J].中国药房,2005,16(3):194-196. 被引量:17
  • 5孔晓东.药物经济学:概念、方法和应用[J].国外医学(药学分册),1994,21(1):13-18. 被引量:429
  • 6唐显军.坎地沙坦——血管紧张素受体拮抗剂的研究进展[J].心血管病学进展,2004,25(3):172-175. 被引量:33
  • 7Ji H, Leung M, Zhang Y, et al.Differential structural requirements for specific binding of hon- peptide and peptide antagonists to the AT1 angiotensin receptor and identification of amino acidresidves that determine binging of the antibypertensive drug losartan[J].J Biol Chem, 1994, 269: 533.
  • 8Timmermans PB.Angiotensin Ⅱ receptor antagonists an emerging new class of cardiovascular th- erapeutics[J].Hypertens Res, 1999, 22( 2): 147.
  • 9Timmermans PB.Pharmacological properties of angio-tensin Ⅱ receptor antagonists[J].Can J Cardiol, 1999, 15( F): 26.
  • 10Kloner RA, Weinberger M, Pool JL, et al.Comparative effects of candesartan cilexetil and amlodipine in patients with mild systemic hypertension, comparison of candesartan and amlodipine for safety, tolerability and efficacy ( CASTLE) study investigations[J].Am J Ca-rdiol, 2001, 87( 6): 727.

二级参考文献14

  • 1胡晋红 杨樟卫.1999年我国药物经济学研究的回顾和评价[J]..中国药学年鉴[C].,2000.76.
  • 2Degli EE, Berto P, Ruffo P, et al. The PANDORA project: result of the cost of illness analysi. J Hum Hypertents. 2001. 15:329-334.
  • 3Degli EE, Sturani A, Degli EL, et al. Pharmacoutilization of antihypertensive drugs: a model of analysis. Int J Clin Pharmacol Ther ,2001,39:251-258.
  • 4Johannesson M, Dahlof B, Lintholm LH, et al. The cost-effectiveness of treating hypertension in elderly people-an analysis of the Swedish TrialOld Patients with Hypertension (STOP Hypertension). J Intern Med ,1993,234 : 317-323.
  • 5Cost effectiveness of combination therapy. Based on a presentation by Daniel Hilleman, Pharm D. Am J Manag Care , 1999, 5( Suppl 7):S449-454.
  • 6Dunn EC, Small RE. Economic of antihypertensive therapy in the elderly. Drugs Anging ,2001, 18: 515-525.
  • 7Pearce KA, Furberg CD, Psaty BM, et al. Cost-mininization and the number need to treat in uncomplicated hypertension. Am J Hypertens,1998, 11:618-629.
  • 8Ramsey SD, Neil N, Sullivan SD, et al. An economic evaluation of the JNC hypertension guidelines using data from randomized controlled trial. Am Board Fam Prac, 1999, 12: 105-114.
  • 9Elliott WJ, Weir DR, Black HR. Cost-effectiveness of the lower treatment goal (of JNC VI) for diabetic hypertensive patients. Arch Intern Med, 2000, 160: 1277-1283.
  • 10Sheikh Ms, Nicar MJ, Schiller LR.Gastrointestinal absorption of calcium from milk and calcium salts[J].New England Journal of Medicine, 1987,317:532.

共引文献1943

同被引文献30

引证文献11

二级引证文献57

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部