黑沙蒿黄酮类化学成分研究

Studies on flavonoids from herb of Artemisia ordosica

目的:研究黑沙蒿的化学成分。方法:采用薄层色谱及硅胶柱色谱法分离纯化,波谱法进行化学成分结构鉴定。结果:从乙醇提取物中分离并鉴定了8个黄酮类化合物,分别为:5-羟基-7,4′-二甲氧基二氢黄酮(Ⅰ),5-羟基-7,4′-二甲氧基黄酮(Ⅱ),5,4′-二羟基-7-甲氧基黄酮(Ⅲ),5,7-二羟基-6,4′-二甲氧基黄酮(Ⅳ),5,4′-二羟基-7-甲氧基二氢黄酮(Ⅴ),5,3′,4′-三羟基-7-甲氧基二氢黄酮(Ⅵ),5,7-二羟基-3′,4′-二甲氧基黄酮(Ⅶ),5,3′,4′-三羟基-7-甲氧基黄酮(Ⅷ)。结论:所有化合物均为首次从该植物中分得。

Objective： To study the chemical constituents of Arterrdsia ordos/ca. Method： The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spectra and physico-chemical properties. Result： Eight flavonoids were obtained and identified as 5-hydroxy-7, 4＇-dimethoxyflavanone, 5-hydroxy-7, 4＇-dimethoxyflavone, 5, 4＇-dihydroxy-7- methoxyflavone, 5, 7-dihydroxy-6, 4＇-dimethoxyflavone, 5, 4＇-dihydroxy-7-methoxyflavanone, 5, 3＇, 4＇-trihydroxy-7-methoxyflavanone, 5, 7-dihydroxy-3＇, 4＇-dimethoxyflavone and 5, 3＇, 4＇-tfihydroxy-7-methoxyflavone. Condusion： All the compounds were obtained from A. ordosica for the first time.