手术治疗的良性前列腺增生患者PSA水平增高的相关因素分析

The analysis of correlated factors about the serum prostate specific antigen in the benign prostatic hyperplasia patients who had received operation

目的:了解手术治疗的良性前列腺增生患者PSA水平增高的相关因素。材料和方法:选取手术治疗的良性前列腺增生患者共369例,取患者的PSA、前列腺体积、残余尿、最大尿流率及国际前列腺症状评分(IPSS)共5项指标进行相关性分析。结果:手术治疗的良性前列腺增生患者血清PSA水平与前列腺体积和年龄呈显著正相关。患者的IPSS与血清PSA水平具有一定的正相关性。患者的PSA与残余尿量和最大尿流率均无明显相关性。结论:在影响血清PSA的相关因素中,年龄、前列腺体积对血清PSA的水平起决定性作用;IPSS可能在一定程度上和PSA的水平相关。

Objective： To study the correlated factors about the serum prostate specific antigen in the benign prostatic hyperplasia patients who had received operation. Menthods： A total of 369 inpatients with benign prostatic hyperplasia who had received operation were analyzes retrospectively. Their PSA, prostate volume, residual urine, maximum urine rate of flow and international prostate symptom score （IPSS） were analyzed. Results： In the benign prostatic hyperplasia patients, the serum PSA is positively correlated with the age and prostate volume. IPSS is possiblely correlated with PSA, while there is no obvious correlation between serum PSA and residual urine or maximum urine rate of flow. Conclusions ： Among these related factors affecting serum PSA, the age and prostate volume play a decisive role. Exact IPSS score is positively correlated with PSA in certain degree. However, there is no obvious correlation between serum PSA and residual urine or maximum urine rate of flow.