服用健脾增免中药对耐力运动员免疫机能及有氧运动能力的影响

Effect of Administration of Chinese Traditiional Herbal Preparation for Invigorating Spleen and Strengthening Immunity on Immune Function and Exercise Capacity of Endurance Athletes

目的:观察健脾增免中药对耐力运动员免疫机能、内分泌及有氧运动能力的影响。方法:33名优秀自行车、中长跑运动员随机分为2组,实验组运动员每天早晚空腹服健脾增免中药汤剂2 0 0ml。1个月后,分别采用3H -TdR掺入法、ELISA法、免疫扩散法、放射免疫法、2 90 0心肺功能测试观察两组运动员免疫机能、内分泌激素和有氧运动能力的变化。结果:实验组运动员服用健脾增免中药后,NK细胞活性、辅助性T细胞亚群比值(Th1/Th2 )、IgG、IgA较实验前显著升高(P <0 . 0 5 ,P <0 . 0 1)。实验组男子运动员服药后血睾(T)和血睾/皮质醇(T/C)较实验前显著升高(P <0 . 0 5 ,P <0 . 0 1) ,并与对照组相比有显著差异(P <0 . 0 5 ) ;实验组女子运动员服药后T/C与对照组相比有显著差异(P <0 .0 5 )。实验组男、女运动员VO2 max相对值较实验前显著提高(P <0 . 0 5 ) ,其中男运动员蹬踏最大功率显著提高(P <0 . 0 1)。实验组服药后血清sIL - 2R明显下降(P <0 . 0 5 )。结论:服用健脾增免中药能有效增强耐力运动员的免疫机能,良好地调节其内分泌激素水平,有助于有氧运动能力的提高。

Objective The effects of administration of Chinese traditional herbal preparation for invigorating spleen and strengthening immunity （ISSI） on immune function and exercise capacity of endurance athletes were observed. Methods Thirty - three elite cyclists and runners were randomly divided into two groups： ISSI group and control group. 200ml per dose of ISSI preparation were separately given to each athlete every morning and evening before meals for 1 month. Th1/Th2, NK cytotoxic activity, sIL - 2R, IgG, IgA, IgM, serum testosterone （T） and cortisol （C）, and VO2max were measured. Results After 1 month of treatment, the immune function of ISSI group including NK cell activity, Th1/Th2 and IgG increased significantly （ P 〈 0.05 ）, especially IgA（ P 〈 0.01 ）. T （ P 〈 0.05 ）, T/C （ P 〈 0.01 ） in male ISSI group increased remarkably, and there was significant difference between ISSI group and control group （ P 〈 0.05 ）, T/C of female ISSI group was significantly higher than control group （P 〈 0.05 ）. Relative value of VO2max male and female ISSI group increased remarkably （ P 〈 0.05 ）. The peak power output of male ISSI group increased significantly （ P 〈 0.01 ）, whereas sIL - 2R of ISSI group reduced significantly （ P 〈 0.05 ）. Conclusion It was demonstrated that this Chinese traditional herbal preparation for invigorating spleen and strengthening immunity could effectively improve immunity of elite cyclists and runners, as well as improve aerobic capacity, and regulate the endocrine level.