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如何提高食源性ACE抑制肽活性的探讨 被引量：10

The discussion of how to improve the activity of ACE inhibitory peptides from food
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摘要 就如何提高食源性ACE抑制肽的活性,分别对原料、蛋白酶和分离纯化方法等几方面的选择作了探讨。 With the question how to improve the activity of ACE inhibitory peptides from food. The selection of materials, proteases and the purification methods were discussed respectively.
作者 胡子豪 钟立人
机构地区 浙江工商大学食品生物及环境工程学院
出处 《食品与机械》 CSCD 北大核心 2005年第5期67-69,80,共4页 Food and Machinery
关键词 血管紧张素转化酶 食源性ACE抑制肽 蛋白酶 分离纯化 ACE抑制肽 食源性 活性 分离纯化方法 Angiotensin I-Conerting enzyme ACE inhibitory peptides from food Protease Purification ACE
分类号 TS201 [轻工技术与工程—食品科学]
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参考文献19

  • 1Richard L. Softer., Angiotensin-converting enzyme and the regulation of vasoactive peptides[J]. Annu. Rev. Biochem, 1976(45) :73 - 94.
  • 2Ferreira S. H. A bradykinin-potentiating fractor present in the venom of Bothrops jararaca[J]. Brit J Pharmacoi, 1965(24): 163 - 169.
  • 3D. W. Cushman, H. S. Cheung. Design of potent competitive inhibitors of Angiotensin- Converting Enzyme. Carboxyalkanoyl and Mercaptoalkanoyl Amino Acids[J]. Biochenistry, 1977,16(25) :5484 - 5491.
  • 4Oshima G, Shimabukuro H, Nagasawa K. Peptide inhibitors of angiotensinconverting enzyme in digests of gelation by bacterial collagenase [ J ].Biochimica et biophysica acta, 1979(566) : 128 - 137.
  • 5Susumu Marugama, Hideo Suzuki. A Peptide Inhibitor of Angiotensin I Converting Enzyme in the Tryptic Hydrolysate of Casein [J]. Agric. Biol. Chem., 1982,46(5) : 1393 - 1394.
  • 6Yoshiyuki Saito, Keiko Wanezaki, Akitsugu Kawato. Struture and Activity of Angiotensin I Conerting Ezyme Inhibitory Peptides from Sake and Sake Lees [J]. Biosci. Biotech. Biochem, 1994,58(10) : 1767 - 1771.
  • 7Made Astawan, Mita Wahyuni et al. Effect of Angiotensin I-Conerting Ezyme Inhibitory Substances Derived from Indonesian Dried-salted fish on Blood Pressure of Rats [ J ]. Biosci. Biotech. Biochem, 1995,59 (3) : 425- 429.
  • 8Toshiro Matsui, Eiji Seki, Katsuhiro Osajima et al. Inhibition of Angiotensin I-Conerting Ezyme by Bacillus lichenifonnis Alkaline Protease Hydrolyzates Derived from Sardine Muscle[J]. Biosci, Biotech. Biochem,1993,57(6) :922 - 925.
  • 9Daodong Pan, Yongkang Luo, Masaru Tanokura. Antihypertensive peptidesfrom skimmed milk hydrolysate digested by cell-freeextract of Lactobacillus helveticus JCM 1004 [ J ]. Food Chemistry, 2005,91 ( 1 ) : 123 - 129.
  • 10Hiroyuki Fujita, Masaaki Yoshikawa. LKPNM: a prodruy-type ACE-inhibitory peptide derived from fish protein[J]. Immunopharmacology, 1999(44) : 123 - 127.

二级参考文献29

  • 1Miyoshi S, Ishikawa H, Kaneko T et al. Structures and activity of angiotensin-converting enzyme inhibitors in an alpha-converting enzyme inhibitors inan alpha-zein hydrolysate[J]. Agric Biol Chem,1991,55 (5) : 1313-1318.
  • 2Yoshikawa M,Fujita H, Matoba N et al. Bioactive peptides derived from food proteins preventing lifestyle-related diseases[JJ. Biofactors, 2000, 12(1-4):143-146.
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  • 7Jens Adler-Nissen. Enzymic Hydrolysis of Food Protein[M]. London: London and New York Elsevier Applied Science Publishers, 1986.
  • 8Cushman D W,Cheung H S. Spectrophotometric assay and properties of the angiotensin converting enzyme of rabbit lung[J].Biochem Pharmol, 1971,20 : 1637- 1648.
  • 9Richard L Softer. Angiotensin-converting enzyme and the regulation of vasoactive peptides[J]. Annu Rev Biochem, 1976,45:73-94.
  • 10李青选.牡蛎保健食品及国外开发概况[J].中国海洋药物,1989,(2):47-52.

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食品与机械
2005年 第5期

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