闭锁综合征临床分析

Clinical analysis of locked-in syndrome

目的:探讨闭锁综合征的病因、病理及临床特点,提高对诊断治疗的认识。方法:对经治3例的临床资料进行分析,并复习相关文献。结果:3例病人,女性2例,男性1例,年龄42～72岁,经过MRI检查,结果符合诊断标准。结论:闭锁综合征病因大多为脑血管病,头颅MRI有助确诊,治疗难度大,预后不良。

Objective To explore the etiology, pathological diagnosis and clinical characteristics of locked-in syndrome so as to improve the understanding of diagnosis and treatment. Methods To analyze clinical data of 3 cases and review related documents. Results 3 patients aged from 42 to 72, including two female cases and one male case, were examined by MRI with a satisfactory result. Conclusion Locked-in syndrome is usually caused by cerebral vascular disease. MRI can be applied to diagnose in spite of its difficulty.