3-叠氮甲基-3-甲基氧丁环的合成

Synthesis of 3-Azidomethyl-3-Methyloxetane

以三羟甲基乙烷与碳酸二乙酯为原料,经环化反应合成了3-羟甲基-3-甲基氧丁环(HMM O)。在低温下,HMM O与对甲苯磺酰氯反应生成3-磺酸酯甲基-3-甲基氧丁环(M TM O)。M TM O和叠氮化钠发生叠氮化反应形成叠氮单体3-叠氮甲基-3-甲基氧丁环(AMM O)。三步反应收率分别为76%,96%,85%。用核磁、红外、元素分析和DSC表征了化合物的结构与性能。结构鉴定表明为目标化合物AMM O。

3-Hydroxymethyl-3-methyl oxetane （HMMO） was prepared by the cyclization of raw materials 1, 1,1- tri（hydroxylmethyl ） ethane and dlethyl carbonate. Under lower temperature, 3-methoxytosyl-3-methyl oxetane （MTMO） was synthesized by the reaction of HMMO with 4-toluenesulfonylchlorlde. 3-Azidomethyl-3-methyl oxetane was synthesized by the reaction of MTMO and sodium azide. The yields of the three steps were 76%, 96%,85%, respectively . The structure and properties of AMMO were identified by ^1HNMR,FTIR,elemental analysis and DSC . The results show that final product was target compound. AMMO was an important energetic oxetane monomer . It can conduct steady cationic polymerization.