低聚果糖对小鼠血糖和血脂作用的影响

The effects of fructooligosaccharide on blood sugar and serum triglyceride and cholesterol in mice

目的观察低聚果糖(FOS)对小鼠血糖(G IU)、血甘油三酯(Tg)和血胆固醇(Ch)的影响。方法FOS 0.1g/kg和1g/kg.bw.天,分组ig(灌服)小鼠连续14天后,分别测定血糖、甘油三酯、胆固醇。结果和正常对照组相比,iglg/kg的小鼠Tg、Ch含量下降,G IU含量上升(P<0.01);ig0.1g/kg的小鼠Tg、Ch含量上升(P<0.05),G IU含量上升。结论FOS1g/kg.bw.天×14天的用量,实验小鼠的血脂水平下降,血糖升高。

Objective： To study the effects of fructooligosaccharide （ FOS ） on blood sugar and serum triglyceride （Tg） and cholesterol （ch） in mice. Methods：The mice were randomly divided into three groups（ the control group and two trail groups）. The two trail groups were fed FOS（0.1 g/kg and 1 g/kg · bw · d respectively）for 14d. Subsequently, the blood sugar（glucose） and serum triglyceride and cholesterol were assayed respectively by available commercial kits. Results ： Compared with the cotrol group, the content of Tg and Ch were dropped in ig 1 g/kg group but remarkablely increased in ig 0.1 g/kg group （p 〈 0.05 ）. However, the levels of blood sugar were increased in the two trail groups. Conclusion：The FOS lg/kg · bw · day × 14d can decrease the contents of Tg and Ch and increase the level of blood sugar in mice.