硬膜外阻滞复合异氟醚麻醉时电针对镇静深度的影响

Clinical Study of the Effect of Electro-acupuncture on Depth of Sedation in Epidural-isoflurune Anesthesia

目的：以听觉诱发电位指数(AAI)和脑电双频谱指数(BIS)为镇静深度监测指标，观察硬膜外阻滞复合异氟醚麻醉时电针的影 响。方法：选择择期上腹部手术，实施硬膜外阻滞复合异氟醚麻醉的患者24例。根据异氟醚肺泡最低有效浓度(MAC)随机分为Ⅰ组 (0． 4MAC)、Ⅱ组(0． 6MAC)、Ⅲ组(0． 8MAC)3组。术中针刺合谷、内关穴，记录各个时间点 AAI、BIS 的变化。结果：电针后，3组 BIS 以及Ⅱ组、Ⅲ组 AAI 均无显著差异(P＞0． 05) ；Ⅰ组 AAI 与电针前即刻相比，除在电针时有显著升高(P＜0． 05) ，2min 后恢复，其余各 个时间点均无显著差异(P＞0． 05) 。结论：电针在硬膜外阻滞复合异氟醚麻醉状况下对镇静深度无明显作用。

Objective： To observe the effect of electro-acupuncture on ARX-model auditory evoked potential index（AAI） and bispectral index（BIS）. Methods：Twenty-four adult patients undergoing elective upper abdominal surgery under epidural-isoflurane anesthesia were enrolled in the study. According to minimum alveolar concentration（MAC） of Isoflurane,they were randomly divided into three group： group Ⅰ（0. 4MAC）, group Ⅱ（0. 6MAC） and group Ⅲ（0. 8MAC）. We selected Hegu（LI4）, Neiguan（PC6） and gave electrical stimulation during operation. AAI , BIB were recorded before anesthesia, before insertion, 1, 2, 3, 4, 5, 10, 15, 20 minute after insertion. Results： Comparison with before insertion, there were no significant change in AAI at group II, group III and in BIS between before insertion and after insertion（P〉0. 05）. AAI only rise significantly at group I in 2 minute after insertion（P〈0. 05）. Conclusion：Electro-acupuncture has no effect on sedation.