35～40岁健康人群尿脱氧吡啶酚参考值研究

Urine Deoxypyridinoline Reference Level of the 35～40 Age Group

目的获得佛山市35～40岁健康人群尿脱氧吡啶酚的参考值,为临床监测骨质疏松的发生及骨量丢失提供诊断依据。方法在本地区范围内,随机抽样收集213例正常男性和209例正常女性尿液标本,采用化学发光法检测尿脱氧吡啶酚,紫外酶法检测尿Cr,以nmolDPD/mmolCr比值为单位,对测量结果进行统计学处理。结果35～40岁健康人群尿脱氧吡啶酚参考值男性为1.47～6.52nmolDPD/mmolCr,女性为2.44～8.80nmolDPD/mmolCr,两者有显著性的差别(P<0.01)。结论35～40岁健康人群尿脱氧吡啶酚参考值有性别差异,应用时应区别对待。

Objective To obtain a reference level dinoline for 35-40 age group of urine deoxypyridinoline of the 35-40 age group. Methods Urine samples of 213 males and 209 females were analyzed. Urine deoxypyridinoline level was measured by chemiluminescence and urine Cr was measured by ultraviolet enzyme assay. Results The reference level of urine deoxypyridinoline for 35-40 age old local resident populations was 1.47-6.52 nmol DPD/ mmolCr for males and 2.44~8.80 nmol DPD/mmolCr for females. There was significant difference between the reference level for different sex （P〈 0.01 ）.Coneluslon The reference level of urine deoxypyridinoline for 35-40 age old normal population is different between male and female, therefore the data should be interputed differently for different sex.