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小动物正电子断层扫描仪(Micro-PET)技术概述 被引量:9

Introduction to micro-PET
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摘要 概述基于临床PET技术发展起来的Micro-PET(micro Positron emission tomography)。它可以实现对小动物的活体扫描和定量分析,从而取代传统的解剖大量动物进行实验的方法。它具有空间分辨率高、体积小、造价低等优点,在疾病诊断、药物研究以及基因工程等领域有着广泛的应用前景。国内已有单位(中科院高能所)从事Micro-PET的研发。 To introduce the Micro-PET (micro Positron emission tomography) based on the clinical animal PET scanner. Micro-PET can provide for vivo scan and quantitative analysis of the same animal instead of pooling the data from a large sample, it provides all the advantages of PET for animal studies, along with far superior spatial resolution and a much lower price tag than currently available clinical PET systems and Micro-PET can be widely applied in many fields such as disease diagnosis, pharmacological study and gene engineering. As an example, introduce the micro-PET now manufactured by IHEP.
出处 《中国体视学与图像分析》 2005年第3期174-176,164,共4页 Chinese Journal of Stereology and Image Analysis
基金 中国科学院科研装备研制基金Y2003012资助
关键词 Micro-PET 活体扫描 符合探测 LSO晶体 Micro-PET vivo scan coincidence Detection LSO scintillator
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  • 11,Melcher C L,Schweitzer J S.Cerium-doped lutetium orthosili cate:a fast,efficient new scintillator.IEEE Trans Nucl Sci,1992,39(4):502~505
  • 22,Yamamoto S,Ishibashi H.A GSO depth of interaction detector for PET.IEE E Trans Nucl Sci,1998,45(3):1078~1082
  • 33,Kapusta M,Pawelke J,et al.Comparison of YAP and BGO for high-resoluti on PET detectors.Nucl Instr Meth,1998,A404:413~417
  • 44,Moses W W,Derenzo S E.et al.LuAlO3:Ce-A high density,high speed sci ntillator for gamma detection.IEEE Trans Nucl Sci,1995,42(1):275~279
  • 55,Knoll G F.Radiation detection and measurements.1989:Chapter 17
  • 66,Ryuo T,Makihara S,et al.Radiation detector.U S A Patent,1991,No.5061855
  • 77,Vaquero J J,et al.Performance characteristics of a compact position-s ensitive LSO detector module.IEEE Trans Med Imag,1998,17(6):967~977
  • 8Hume SP,Brown DJ,Ashworth S et al.In vivo saturation kinetics of two dopamine transporter probes measured using a small animal scanner.J Neurosci Methods,1997;76(1):45~51
  • 9Green LA,Gambhir SS,Srinivasan A et al.Noninvasive methods for quantitating blood time-activity curves from mouse PET images obtained with fluorine-18-fluorodeoxyglucose.J Nucl Med,1998;39(4):729~34
  • 10Nikolaus S,Larisch R,Beu M et al.Imaging of striatal dopamine D2 receptor with a PET system for small laboratory animals in comparison with storage phosphor autoradiography:A validation study with 18F-(N-methyl)benperidol.J Nucl Med,2001;42(11):1691~6

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