皮康口服液的质量标准研究

Study on Quality Standard for Pikang Oral Liquid

目的:建立皮康口服液的质量标准。方法:用薄层色谱法对黄芪、赤芍进行定性鉴别,用反相高效液相色谱(RP HPLC)法测定口服液中的芍药苷的含量。结果:薄层色谱斑点清晰,专属性强;芍药苷在0．116-1．16μ范围内呈良好的线性关系,r=0．999 8,平均回收率为98．99％,RSD为0．62％。结论:所建立的方法简便准确、灵敏度高,可用于皮康口服液的质量控制。

Objective： To establish the quality standard for pikang oral liquid. Method： TLC was used for qualitative identification of the astragalus membranaceus and radix paeoniae rubra（RPR）. The content of paeoniflorin in the oral liquid was determined by RP-HPLC. Result： The qualitative identification could separate well. Paeoniflorin showed a good linear relationship in the range of 0.116-1. 16μg （ r = 0.999 8 ）. The average recovery was 98.99% （ RSD = 0.62% ）. Conclusion： The method is simple, accurate and sensitive. It can be used for quality control of pikang oral liquid.