颈椎前路椎体间微创融合器的生物力学实验研究

Biomechanical study on new minimally embedded invasive cervical fusion cage

目的评价植入镍钛记忆合金微创融合器(NiTi-TFC/C)的颈椎节段的稳定性及压缩力学性能。方法采集24只羊颈椎标本随机分为4组,每组6份,四组处理分别为:单取髓核组、自体髂骨植骨组、微创融合器组和钛制融合器组(InterFix)。所有标本进行前路减压,并对后3组进行椎间融合术。分别对各组标本进行生物力学测试并进行比较。结果微创融合器组与钛制融合器组在强度、刚度及扭转力学等方面无显著性差异(P>0.05)。而微创融合器组与自体髂骨植骨组具有显著性差异(P<0.05)。最大承载力为12050N。结论该微创融合器强度大、刚度高、抗扭转能力强,具有良好的抗压能力,为颈椎融合提供新型的融合装置。

Objective To evaluate the stability and compressive mechanical functions of the cervical spine after implanting a new minimally embedded invasive fusion cage made of Nititanium shape memory alloy （NiTi-TFC/C）. Method Anterior cervical discectomies were performed on 24 mature sheep spines which were divided randomly into four groups of six sheep cervical spines each： the discectomy group, the autogenic iliac bone graft group, the NiTi-TFC/C group, and the Inter Fix （Sofamor Danek） group. The stability of each group was tested by experimental stress analysis. Result There was no significant difference between the groups of NiTi-TFC/C and Inter Fix in the biomechanical characters （P〉0.05）. There was significant difference between the groups of NiTi-TFC/C and autogenic iliac bone graft （P〈0.05）. Conclusion NiTi-TFC/C shows effective characters with high strength and stiffness, less depression displacement. It provides a new kind of device for cervical fusion.