瘦素及血脂与中、老年患者非酒精性脂肪肝的关系
被引量:1
摘要
目的探讨瘦素及血脂与中、老年患者非酒精性脂肪肝的关系.方法检测31例非酒精性脂肪肝(简称脂肪肝,FL)和25例无脂肪肝(NFL)中、老年患者空腹血清LP、BG、TC、TG、HDL-C、LDL-C、BUN、ALT、AST及GGT水平,并测量SBP/DBP和BMI等指标.结果BMI、TC、TG、LDL-C及DBP的平均值,FL组明显高于NFL组(P<0.05~0.001).在两组中,血清LP浓度女性皆明显高于男性.但LP在两组之间未显示统计学差异.结论在FL组中,BMI、TC、LDL-C、TG与FL密切相关.
出处
《临床医学》
CAS
2005年第10期29-31,共3页
Clinical Medicine
参考文献13
-
1Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature, 1994,372:425 -432.
-
2Ostlund RE Jr, Yang JW, Klein S, et al. Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates. J Clin Endocrinol Metab, 1996,81:3909 - 3913.
-
3Ma Z, Gingerich RL, Santiago JV, et al. Radioimmunoassay of leptin in human plasma. Clinical Chemistry, 1996,42:942 - 946.
-
4Montague CT, Prins JB, Sanders L, et al. Depot - and sex - specific differences in human leptin mRNA expression: implications for the control of regional fat distribution. Diabetes, 1997,46:342 - 347.
-
5Harmelen VV, Reynisdottir S, Eriksson P, et al. Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes, 1998,47:913 -917.
-
6Dua A, Hennes MI, Hoffmann RG, et al. Leptin: A significant indicator of total body fat but not of visceral fat and insulin insensitivity in African -American women. Diabetes, 1996,45:1635 - 1637.
-
7Moller N, Obrien P, Nair KS. Disruption of the relationship between fat content and leptin levels with aging in humans. J Clin Endocrinol Metab,1998,83:931 -934.
-
8Casabiell X,Pineiro V,Peino R,et al. Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro:dexamethasone and estradiol stimulate leptin release in women, but not in men. J Clin Endocrinol Metab,1998,83:2149 -2155.
-
9Wabitsch M, Blum WF, Muche R, et al. Contribution of androgens to the gender difference in leptin production in obese children and adolescents.J Clin Invest, 1997,100:808 - 813.
-
10Malmstrom R,Taskinen MR,Karonen SL,et al. Insulinincreases plasma leptin concentrations in normal subjects and patients with NIDDM. Diabetologia, 1996,39:993 - 996.
-
1张丽丽,江奕文.2型糖尿病胰岛素抵抗、血脂水平、体重指数与脂肪肝的关系探讨[J].中国社区医师(医学专业),2006,8(14):139-140. 被引量:1
-
2马晓云.糖尿病合并脂肪肝224例分析[J].中国误诊学杂志,2002,2(4):548-549. 被引量:1
-
3李侗曾(编译).抗逆转录病毒治疗可能有助于阻止HIV相关的脑损伤[J].传染病网络动态,2007(12):9-10.
-
4李士新,马小川,李晓莉.非酒精性脂肪肝的多因素分析[J].延安大学学报(医学科学版),2005,3(1):10-11. 被引量:2
-
5刘军,陈影,刘芳,徐东丽,姚庆姑.肝脏脂肪浸润程度与胰岛素抵抗的相关性研究[J].临床内科杂志,2004,21(2):120-122. 被引量:9
-
6张军汉,傅国琴,翟惠虹,郭文伟,张林慧.血糖正常者非乙醇性脂肪肝与高胰岛素血症的相关性[J].第四军医大学学报,2006,27(6):524-526. 被引量:1
-
7李会杰,刘亚玲,井永敏,张英泽,王振昊,闫金成.自分泌骨桥蛋白在Nfl+/-小鼠破骨细胞功能增强中的作用[J].中华骨科杂志,2013,33(11):1147-1154.
-
8杨金花,刘彦慧,黄春平.护理管理者领导力测评工具中文版信效度研究[J].中国实用护理杂志,2012,28(29):1-4. 被引量:21
-
9李士新,马小川,李晓莉.非酒精性脂肪肝52例多因素分析[J].陕西医学杂志,2005,34(9):1122-1124. 被引量:3
-
10裴彦祯,韩涛,马晓艳,李莹,邢晶,宋佐莉.HBsAg及HBVDNA定量水平在慢性乙型肝炎、肝硬化和肝癌患者中的变化[J].中华肝脏病杂志,2011,19(10):743-746. 被引量:53