再生丝素蛋白水溶液静电纺丝性能的研究

A study on the electrospinning process from regenerated silk fibroin aqueous solution

运用静电纺丝方法,从再生蚕丝素蛋白水溶液中制得了念珠状的、圆形的或扁平状的超细再生丝,纤维的直径在100～900nm之间,平均为700nm.溶液浓度和电压强度对静电纺丝性能的影响很大,当纺丝液浓度为28%(质量分数),电压为20kV,喷射距离为 11cm时,可制得具有光滑表面的圆形再生丝.大角X衍射(WAXD)测试结果认为,静电纺再生丝中含有α螺旋和β-折叠结构,但其结构既不同于无定型丝素膜,也不同于天然蚕丝纤维,介于二者之间.

By using electrospinning technique, beaded, cylinder shaped and ribbon like ultra-fine silk fibroin （SF） fibers were obtained from its concentrated aqueous solution under different processing conditions. These fibers had an average diameter of 700nm and were characterized by scanning electron microscopy （SEM） and wide-angle X-ray diffraction （WAXD）. A kind of SF fiber with the structure between amorphous film and nature silk was found. The morphology and the secondary structure of the as-spun SF fibers were strongly influenced by the solution concentration, as well as the processing voltage.