腹水超滤浓缩腹腔回输治疗难治性腹水的疗效

Ultrafiltration and Reinfusion into Abdominal Cavity to Treat Refratory Ascites

目的探讨应用WLFHY500型伟力腹水超滤浓缩回输系统行腹腔回输治疗难治性腹水的临床疗效及对肝肾功能的影响。方法常规进行腹腔穿刺与超滤回输系统连接形成抽吸-超滤-浓缩-回输状态对各类顽固性腹水进行治疗。结果共治疗36例,61次。治疗后的患者在体重、腹围、腹压、24h尿量方面与治疗前比差异有显著性(P<0.01)。腹水浓缩回输前后血尿素氮、谷丙转氨酶及总胆红素没有变化(P>0.05),血浆总蛋白、白蛋白增加(P<0.01),血肌酐下降(P<0.01)。超滤浓缩后的腹水较超滤前腹水中的总蛋白、胆红素增加(P<0.01),电解质无变化(P>0.05)。临床总有效率为78.57%。结论本组资料表明腹水超滤浓缩行腹腔回输是一种安全可靠、简便有效的方法。

Objective The aim of tiffs study is to examine the clinical effective rate of ultrafiltration and intraperitoneal reinfusion of aseites to treat refractory aseites with the model WHFHY-500 weili （powerful） computer aseites extra filtration concentration system（AEFCS）. To survey the effect of tiffs treatment to renal function and liver function. Methods Routine abdominal paracentesis was conducted. A closod-cyele AEFCS was built. Results We performed 61 ultrafiltration and reifusion in 36 patients during hospitalization. The observation items were the weight,abdominal perimeter,abdominal pressure and urine volume per 24 h. There items were statistical differences as compared with those before treatment （ P 〈 0. 01 ）. The before treatment and later, the ureanitrogen, the glutamic-pyruvic transaminase（GPT） and the total bilirubin did not change （ P 〉 0.05 ）. The total protein and albumen of plasma increased （P 〈0.01 ） ,the level of Cr decreased （P 〈 0.01 ）. The total protein and bilirubiu were increased which ascites by later ultrafiltration （P 〈0.01 ）, and the electrolyte did not change （ P 〉 0.05 ）. The total clinical effective rate was 78.57%. Conclusion The method of ultrafiltration and infusion of ascites to treat refractory aseites is asafe,easy and effective method.